There are a few reasons to work on the bottom first, the most obvious being that you can trigger our beloved cascades more easily there. Even jelly higher up in the puzzle will not be safe. More importantly, though, the bottom of this board is covered in frosting that can be easily penetrated. Get rid of it quickly to open up the board for more cascades and special candy formation.
You do not need to worry about the candy bombs right away, since they are set to go off one turn before the end of the level, but removing them with special candies will also help you get rid of jelly at the same time. Once you have successfully opened up one or both sides of the board, make striped candies and look for any opportunity to make a colour bomb. The combination of these two will help you decimate the jelly in no time.
Beware the moon scale and take moon struck to your advantage.