Instead of concentrating on creating two colour bombs to be combined, which can be difficult because you have to create two and you will have to set them up side by side, focus on removing the icing. Wrapped candies, wrapped+wrapped combination, wrapped+striped combination, colour bomb+stripe are helpful here.
When you have candies in the right column, try to get a vertical striped candy there to break the colour bombs from the marmalade.
Try to combine colour bombs with a regular candy to reduce the number of colours in play and increase the chance to create other colour bombs.
This level is similar to level 250 that the liquorice swirls are in the middle of the board. However, in this level, the 6th column is empty.
This level, level 428 and level 1142 are currently one of the hardest levels with 4 colours.
This was one of the hard four colour levels. People thought the Dreamworld counterpart of this level would be an extremely hard level because of the addition of a 5th colour, and it turned out to be like most others.