The obvious approach to this level would be to wait until you only have 15 moves before unlocking the sugar chest.
Then try to use those remaining moves to clear the column and let the ingredients drop. But there are not really enough moves for this methodical approach. Better to play loose, expect and hope for luck.
You really need to fluke a colour bomb + striped candy combination here at the right time to take out all the bombs. Go for all combinations and if you do not get lucky, there is always another chance.
The simplest approach is to destroy the icing on the right first, before you unlock the sugar chest on the left with the third key. Generate as many horizontal striped candies as possible and use them strategically on the multi-layer icing. Wrapped/striped combinations are really useful here—just make sure you maximise their usefulness by having them take out as much icing as possible. Pay attention to the fact that each icing in the stack has one more layer than the one above it, so you will have to hit the bottom one four times. Avoid hitting the third key until you have cleared all the icing on the right, otherwise you will have to deal with the bombs (unless you have 15 or fewer moves remaining, then it does not matter). Also, do not forget that the fruits will not drop in the right column until you get the fourth key—which will end up at the bottom of the column of bombs on the left when you use the third key. So if you can set up having a horizontal striped candy in the bottom row, or a striped/wrapped combination in the bottom two rows, you will make your life simpler. If you have cleared all the icing in the right column, then when you activate the fourth key, you will complete the level. The level is really not that hard if you use this strategy.